amyloid :

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amyloid

a mi law id

  • n  a non-nitrogenous food substance consisting chiefly of starch; any substance resembling starch
  • n  (pathology) a waxy translucent complex protein resembling starch that results from degeneration of tissue
  • s  resembling starch

  • Clusterin may be involved in helping to clear away the amyloid that forms in the brain; but another variant of the gene may also allow amyloid to form fibrils, the sticky protein .
  • Selkoe and other Amyloid People see the disease process as a biochemical cascade; the event that triggers the cascade, they believe, is the accumulation of beta amyloid.
  • To their great surprise, they discovered that beta amyloid was a fragment of a much larger protein, which came to be known as the amyloid-precursor protein, or .
News & Articles

  • Existing medications may help treat Alzheimer's
    NEW YORK, June 15 (UPI) -- Drugs used for hypertension or insomnia may also help reduce the development of amyloid plaques, which is linked to Alzheimer's, U.S. researchers say.
    June 15, 2013 - UPI
  • Study Measures Changes In Brain Proteins In Alzheimer's Patients For First Time
    April Flowers for redOrbit.com - Your Universe Online A significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer's disease and healthy family members who do not have it has been measured by researchers at Washington University School of Medicine in St. Louis. Researchers have long known that a protein fragment called amyloid beta builds up ...
    June 13, 2013 - redOrbit
  • Mice Research Suggests Common Drugs May Lower Risk of Alzheimer’s
    New research on mice suggests that many commonly prescribed drugs are capable of reducing the onset and progression of Alzheimer’s disease. Led by Giulio Maria Pasinetti, M.D., Ph.D., researchers at The Mount Sinai Medical Center used a computer algorithm to screen 1,600 commercially available medications to assess their impact on the brain accumulation of beta-amyloid. [...]
    June 13, 2013 - Psych Central
Quotes

  • Richard Nixon in Malaya
    We have been ignoring other pathways that may be essential to treating Alzheimer's disease. We've been basically tracking one way to approach therapy, which is to eliminate amyloid protein from the brain,Nixon said.
  • Andrew Luster in Hindu
    By showing that microglia have a protective role in helping remove amyloid-beta from the brain, our findings suggest that enhancing the accumulation of these cells may be beneficial to patients with early-stage Alzheimer's disease,says Andrew...
  • Alan Carpenter in Atlanta Journal Constitution (registration)
    People with Alzheimer's had a significant 'signal' in the brain in areas known from autopsy where amyloid tends to deposit,confirmed Alan Carpenter, vice president of business development at Avid Radiopharmaceuticals in Philadelphia, which...

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