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• s  burdened by cares
  all ye that labor and are heavy-laden"-Matt.11:28
• s  bearing a physically heavy weight or load
  a heavy-laden cart

• When the heavy-laden monster finally rose, the crew opened the hatch, only to see the ground still hugging them.
• The heavy-laden uterus can press too hard on the big vessel (vena cava) carrying blood back to the heart, and thus cause a dangerous drop in blood pressure, or shock.
• Many airplanes, especially heavy-laden bombers, are launched by booster (jato) rockets whose powerful push gets them into the air without too long a take-off run.

• care-laden
• burdened
• loaded down