genetic defect :

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  • Scientists Silence Extra Chromosome In Down Syndrome Cells
    An anonymous reader writes "Scientists have silenced the extra copy of a chromosome that causes Down syndrome in laboratory stem cells, offering the first evidence that it may be possible to correct the genes responsible for the disorder. The discovery provides the first evidence that the underlying genetic defect responsible for Down syndrome can be suppressed in cells in culture." Read more of ...
    July 18, 2013 - Slashdot
  • Scientists show proof-of-principle for silencing extra chromosome responsible for Down syndrome
    Scientists have established that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment. The discovery provides the first evidence that the underlying genetic defect responsible for Down syndrome can be suppressed in cells in culture.
    July 17, 2013 - Science Daily

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