Doctors have hesitated to use the plumber's method because they feared that peeling off the inner lining (endothelium), along with the dead tissue, calcium and fatlike substances .
Laughter increases blood flow by causing the inner lining of blood vessels (the endothelium) to expand, according to a small study of healthy moviegoers who were shown both funny .
What it does: Develops drugs that act on the endothelium, a layer of cells lining blood vessels that acts as a selective barrier between the bloodstream and surrounding tissue.