amethopterin :

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  • n  toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis

  • Most gratifying and surprising was the discovery that amethopterin, after years of use in acute leukemia, was effective against choriocarcinoma.
  • There were as many dissents as there were theories, and since so few drugs cure viral infections, the very fact that potent anti-cancer drugs such as amethopterin (Methotrexate .

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