n toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis
Most gratifying and surprising was the discovery that amethopterin, after years of use in acute leukemia, was effective against choriocarcinoma.
There were as many dissents as there were theories, and since so few drugs cure viral infections, the very fact that potent anti-cancer drugs such as amethopterin (Methotrexate .