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• n  a state of mental disturbance and disorientation
• n  the act of disturbing the mind or body

• And while the Columbine massacre happened on student turf and was the product of obvious derangement, it did not carry the generalized threat of holy war against all Americans at .
• After the experiment in systematic derangement ends in scandal and squalor, Claude makes his way back to Cambon.
• Street Kings lives in the narrow cracks between dedication and derangement, accommodation and corruption, and leaves it to audiences to figure out where their rooting interest lies.

• mental unsoundness
• unbalance
• upset
• overthrow

News & Articles

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• Dubya Obama
  It wasn’t long ago that conservatives were complaining about Bush Derangement Syndrome. This had to do with the way otherwise intelligent people lost any sense of reason or proportion when it came to anything George W. Bush-related. The result was a poisoned debate on national security, and the vilification...
  June 8, 2013 - New York Post

Quotes

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• Tom Frank in Kansas City Star
  For instance, Thomas Frank, something of a guru to angry liberals, wrote in his book What's the Matter with Kansas?: "People getting their fundamental interests wrong is what American political life is all about. This species of derangement is the...
• Lyndall Gordon in guardian.co.uk
  ...the empathetic way that Gordon tells the tale opens out to us the intolerable situation that Elizabeth was in and the sensitivity of Wollstonecraft's response: "When Mary came to nurse Bess she was sliding into derangement and craving...