Each nephron is made up of a tuft of microscopic blood vessels, called a glomerulus, and each of these has a minute tubule at tached (see diagram, right).
Misplaced protein causes heart failure Decreasing the density of microtubules inside heart muscle cells prevents the abnormal localization of a critical protein called junctophilin 2 (JP2), and protects mice from heart failure, new research has found. Conversely, increasing microtubule density causes abnormal localization of JP2, which leads to loss of normal heart cell function and ultimately heart failure.
March 6, 2014 - Science Daily