imipramine
- n a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression
- As other feel-good pills followedTofranil (imipramine) for depression, Miltown and Equanil (meprobamate) for psychosis, Valium (diazepam) for severe anxiety and lithium for .
- By tinkering with the chemical structure of antihistamines, a Swiss psychiatrist, Ronald Kuhn, created a drug called imipramine, first of the so-called tricyclic antidepressants.
- With the introduction of strikingly effective antipsychotic drugs such as chlorpromazine and imipramine in the 1950s, the popularity of shock treatment began to wane.