- n a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression
- With the introduction of strikingly effective antipsychotic drugs such as chlorpromazine and imipramine in the 1950s, the popularity of shock treatment began to wane.
- As other feel-good pills followedTofranil (imipramine) for depression, Miltown and Equanil (meprobamate) for psychosis, Valium (diazepam) for severe anxiety and lithium for .
- By tinkering with the chemical structure of antihistamines, a Swiss psychiatrist, Ronald Kuhn, created a drug called imipramine, first of the so-called tricyclic antidepressants.
News & Articles
- Hiding in Plain Sight: Finding New Targets for Old Drugs
In late 2011, mice with lung cancer had their tumors reduced by an antidepressant called imipramine. The basis of the study was the idea that the cancer switches certain genes on, while imipramine turns the same genes off. A neat ...
Nov. 14, 2013 - Wired News