amphotericin :

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  • n  an antibiotic and antifungal agent

  • Cryptococcal meningitis was always fatal until the antifungal drug, amphotericin B, came into use six years ago.
  • The worst, victims agree, is amphotericin B, known as "Ampho the Terrible" to those who have to have it injected into the base of their skull for meningitis.
  • In the beginning, treatment consisted of high doses of intravenous amphotericin B, which patients quickly dubbed "amphoterrible" because of its nauseating side effects.

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