agonist agonist  /ˈæ ɡə nɪst/


  1. (n) the principal character in a work of fiction
  2. (n) someone involved in a contest or battle (as in an agon)
  3. (n) a muscle that contracts while another relaxes
  4. (n) (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction


  • Like methadone, the compound that activates D1 appears to be what is known as a partial agonist.


  1. Concert Pharmaceuticals Initiates Phase 1 Clinical Trial of CTP-354, a Potential Treatment for Spasticity and Pain

    Concert Pharmaceuticals, Inc. today announced that it has initiated a Phase 1 clinical trial with CTP-354. CTP-354 is a novel GABAA receptor subtype-selective modulator that has demonstrated no sedation at therapeutic doses in preclinical models in contrast to existing GABAA receptor non-selective agonists, such as benzodiazepines.
    on June 10, 2013     Source: Business Wire via Yahoo! Finance

  2. Fear learning studies point to a potential new treatment for PTSD

    An opioid receptor agonist can reduce PTSD-like symptoms in an animal model. Additional data from humans strengthen the case for opioid receptors' involvement in regulating fear learning.
    on June 6, 2013     Source: EurekAlert!


  • "In total, there are about 5,000 deaths a year due to asthma, whether or not a person is taking a long-acting beta-agonist," said Edwin Salpeter, the JG White Distinguished Professor of Physical Sciences Emeritus at Cornell, who led the...
    on Jun 19, 2006 By: Edwin Ernest Salpeter Source:

Word of the Day
cynic cynic
/ˈsɪ nɪk /