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• n  a small island

• Past attempts to implant fetal islet cells failed because a small percentage of these cells have antigenic markers that trigger an immune response.
• For many I-Kiribati, the clincher for the reality of climate change is the disappearance of Bikeman, an islet that once sat about a half-hour's canoe ride southeast of Betio.
• Once 90% of the islet cells are destroyed, the body is no longer able to regulate blood-sugar levels and the patient develops the classic symptoms of diabetes.

• isle

News & Articles

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• New Data on Islet Autoantibodies in Young Children Defines Early Type 1 Diabetes Development
  --Long-term study reveals that multiple islet autoantibodies in young children indicate a high risk of developing type 1 diabetes within 10 years, clarifying the window for potential prevention strategies--NEW YORK, June 19, 2013 /PRNewswire-USNewswire/ -- A decade-long JDRF-funded study led by the Institute of Diabetes Research in Helmholtz Zentrum München, Germany, is providing a deeper ...
  June 19, 2013 - PR Newswire via Yahoo! News
• Markers of beta-cell dysfunction associated with high rate of progression to type 1 diabetes
  The majority of children at risk of type 1 diabetes who developed 2 or more diabetes-related autoantibodies developed type 1 diabetes within 15 years, findings that highlight the need for research into finding interventions to stop the development of multiple islet autoantibodies, according to a study in the June 19 issue of JAMA.
  June 18, 2013 - EurekAlert!

Quotes

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• James Shapiro in Science Daily (press release)
  This really shows that islet transplantation can be tremendously successful in protecting against hypoglycemic unawareness,says Dr. Shapiro.