The good news is that they need the genes to churn out their proteins for a only brief period of time, so using less virulent viruses, such as the adenovirus (responsible for the .
Out of 93 gene-therapy trials using adenovirus, it was recently revealed, there were 691 instances of adverse effects.
What makes the adenovirus ideal for the task is precisely the reason colds make us so miserable once inside a host, the cold virus infects cells and starts to replicate quickly.
Scientists identify promising antiviral compounds Scientists have identified two promising candidates for the development of drugs against human adenovirus, a cause of ailments ranging from colds to gastrointestinal disorders to pink eye. The researchers sifted through thousands of compounds to determine which might block the effects of a key viral enzyme they had previously studied in atomic-level detail.
July 2, 2013 - Science Daily