AZT as a single agent, and perhaps some of the nucleoside analogs did prolong life, and have prolonged lives.
The likeliest candidates: Lesch-Nyhan syndrome; adenosine deaminase deficiency, an immune disorder of the type that killed the famous "Bubble Boy"; and purine nucleoside .
Merck’s Investigational HIV Therapy, Doravirine (MK-1439), Demonstrates Antiviral Activity in Phase 2B Study of ... Merck , known as MSD outside the United States and Canada, today presented data from the dose-ranging portion of an ongoing Phase 2B clinical trial of doravirine, the company’s investigational next-generation, non-nucleoside reverse transcriptase inhibitor , at the 21st Conference on Retroviruses and Opportunistic Infections .
March 5, 2014 - Business Wire via Yahoo! Finance