Treatment begins with aspirin (followed in some cases by indomethacin or phenylbutazone but no hormones) to ease the pain, then heat, applied by moist packs, and physiotherapy.
PPA, alone or together with other drugs, such as monoamine oxidase inhibitors (antidepressants) or indomethacin (an antiarthritic), can induce severe episodes of hypertension.
To help correct the condition, the children were given the drug indomethacin, which decreases the body's production of a chemical that keeps the shunt open.
Iroko Pharmaceuticals Announces Acceptance for NDA Filing of Lower Dose Submicron Indomethacin for the Treatment of ... Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to scientific advancements in analgesia, announced that the U.S. Food and Drug Administration has accepted for review the New Drug Application for lower dose submicron indomethacin, a non-steroidal anti-inflammatory drug , for the proposed indication of treatment of mild to moderate acute pain in adults.
July 16, 2013 - Business Wire via Yahoo! Finance