immunosuppression :

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  • n  lowering the body's normal immune response to invasion by foreign substances; can be deliberate (as in lowering the immune response to prevent rejection of a transplanted organ) or incidental (as a side effect of radiotherapy or chemotherapy for cancer)

  • At best, though, immunosuppression is a blunderbuss approach that also leaves the body unshielded against lethal germs and sometimes apparently cancer.
  • Starzl stopped operating while he and his colleagues worked on a less hazardous method of immunosuppression, using antilymphocyte serum or globulin extracted from horses into which .
  • Serum that inhibits the production and action of lymphocytes, the cells responsible for rejection, may cause severe reactions; immunosuppression, which is now the mainstay of .
News & Articles


  • Glenn in EurekAlert (press release)
    It's autologous, we don't need to worry about rejection of tissue, and immunosuppression,says Glenn Winnier of Pharmafrontiers, a company in Woodland, Texas.
  • Thomas Okarma in Reuters
    A reduction in the requirement for immunosuppression decreases the potential for untoward side effects that are common with those types of drugs,said Thomas Okarma, the company's chief executive officer, in a statement.

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