hypercholesterolemia :

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  • n  the presence of an abnormal amount of cholesterol in the cells and plasma of the blood; associated with the risk of atherosclerosis

  • Working with rabbits afflicted with familial hypercholesterolemia, a metabolic disorder, Wilson is trying to transfer good genes into defective hepatocytes, cells in the liver that .
  • They are a classic sign of severe familial hypercholesterolemia (FH), a genetic defect that leads to a tremendous buildup of cholesterol in the blood.
  • People with this condition, called familial hypercholesterolemia (FH), have 25 times the normal risk of heart disease.
News & Articles

  • Esperion Therapeutics, Inc. Announces Pricing of Initial Public Offering
    Esperion Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing and commercializing first-in-class, oral, low-density lipoprotein cholesterol lowering therapies for the treatment of hypercholesterolemia, today announced the pricing of its initial public offering of 5,000,000 shares of its common stock at a price to the public of $14.00 per share.
    June 26, 2013 - Business Wire via Yahoo! Finance
  • Low-income uninsured U.S. adults less likely to have chronic conditions compared with medicaid enrollees
    Compared with adults already enrolled in Medicaid, low-income uninsured adults who may be eligible for Medicaid under the Affordable Care Act were less likely to have chronic conditions such as hypertension, diabetes, and hypercholesterolemia, although those with 1 of these conditions were less likely to be aware they had it or to have the disease controlled, according to a new study.
    June 23, 2013 - Science Daily

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