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• n  inflammation of the endocardium and heart valves

• Diseases against which penicillin is effective but not fully tested: syphilis, actinomycosis, bacterial endocarditis.
• The evidence (from a British military hospital): twelve cases of leg ulcers, carbuncles, boils, colitis, bacterial endocarditis, gonorrhea, septicemia which vivicillin failed to .
• Briton Hadden, 31, of Manhattan, co-founder of PTI; of a streptococcus infection of the blood stream which became fatal when endocarditis developed.

News & Articles

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• No Mortality Benefit For Surgery In Prosthetic Valve Endocarditis
  In the first five years after valve replacement approximately 3-6% of patients will develop prosthetic valve endocarditis (PVE). These patients are much more likely to die. Now a large observational study — the first of its type — has found that surgery is no better than medical therapy in reducing mortality in these patients. The report from the ICE-PCD (International Collaboration on ...
  July 15, 2013 - Forbes
• 1-year mortality remains high in patients with prosthetic valve endocarditis
  Prosthetic valve endocarditis (inflammation and infection involving the heart valves and lining of the heart chambers) remains associated with a high one-year mortality rate and early valve replacement does not appear to be associated with lower mortality compared with medical therapy.
  July 15, 2013 - EurekAlert!
• One-Year Mortality Remains High in Patients with Prosthetic Valve Endocarditis
  Prosthetic valve endocarditis (inflammation and infection involving the heart valves and lining of the heart chambers) remains associated with a high one-year mortality rate and early valve replacement does not appear to be associated with lower mortality compared with medical therapy.
  July 15, 2013 - Newswise