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• n  a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)

• Both inhibit a messenger in the inflammatory cascade known as the tumor necrosis factor (tnf).
• Immunex's treatment, which worked so effectively for Lindagail Dixon, consists of genetically engineered proteins that sop up excess tnf, interrupting the cycle of destruction.

• tumor necrosis factor
• tumour necrosis factor
• TNF

News & Articles

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• CDR recommends self-injectable subcutaneous formulation of first non-anti-TNF biologic treatment available in both ...
  CDR recommends self-injectable subcutaneous formulation of first non-anti-TNF biologic treatment available in both intravenous and subcutaneous formulations to be reimbursed for Canadians with moderately ...
  Aug. 12, 2013 - CNW Group via Yahoo! Finance

Quotes

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• Paul Emery in StreetInsider.com (subscription)
  These study results are very promising for RA patients who need a variety of treatment options, particularly when they have failed to achieve adequate pain and symptom relief with anti-TNF therapies,said Professor Paul Emery, lead study...
• Ian Woosnam in Telegraph.co.uk
  The drug, called TNF, I think, was developed about 10 years ago for rheumatoid arthritis. Then they began using it for ankylosing spondylitis, which I have,Woosnam explained. "It's a bit like an insulin injection. You do it yourself....
• Doug Collins in ESPN
  Where you do not have dialogue, there is chaos. There is need to put in place the TNF so that labour, business and Government sit around a table and discuss issues which affect our country so that we come up with a holistic approach to our... Paurina Mpariwa http://www.google.com/url?q=http://en.wikipedia.org/wiki/Paurina_Mpariwa&source=dictionary&usg=AFQjCNH5_ZEd683am0zViNBRzjspjuxPPQ AllAfrica.com http://www.google.com/url?q=http://allafrica.com/stories/200612290630.html&source=dictionary&usg=AFQjCNGNWWM4WH6dM-uYV2lCaTGdUAsg2w Dec 29, 2006 100495 133423 tnt Through a TNT spokesman, Collins said Thursday, I have spoken with Bulls management recently about their head coaching vacancy and will resume conversations after the conclusion of my work for TNT in the Western Conference finals. There is no...