phenylalanine :

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phenylalanine


  • n  an essential amino acid found in proteins and needed for growth of children and for protein metabolism in children and adults; abundant in milk and eggs; it is normally converted to tyrosine in the human body

  • In phenylketonuria (PKU), an infant is unable to metabolize phenylalanine (one of the basic components of many proteins) and is in danger of severe mental retardation.
  • The conclusion was inescapable: in the genetic code, Nirenberg's triplet had to signify phenylalanine.
  • Aspartame contains phenylalanine and will carry a warning on the label.
News & Articles

  • Merck Announces Positive Outcome of IIIb Study for Kuvan
    -- Primary endpoint met in SPARK study: significant increase in phenylalanine tolerance demonstrated after 26 weeks of the study in children less than 4 years of age with phenylketonuria and responsive to Kuvan treated with Kuvan plus a phenylalanine-restricted diet, versus diet alone -- SPARK study was conducted as a post-authorization measure and results will be submitted to EMA this year ...
    April 24, 2014 - PR Newswire via Yahoo! Finance

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