monoclonal monoclonal  /ˌmɑ nə ˈkloʊ nəl/

Definition(s):

  1. (n) any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules
  2. (adj) forming or derived from a single clone

Usage(s):

  1. Public company based in Melbourn, England CEO: Peter Chambr What it does: Develops human monoclonal antibodies as treatment for disease.
  2. The monoclonal antibodies used against cancer are proteins designed to latch on to a specific molecule on the surface of a tumor cell, while leaving normal cells untouched.
  3. To come up with a monoclonal antibody to fight cancer, Tepper's group uses a strain of mice whose immune systems are genetically engineered to generate human antibodies.

News

  1. Bristol-Myers Squibb and AbbVie Announce Progression-Free Survival Data from Phase 2 Open-Label Study of ...

    Bristol-Myers Squibb Company and AbbVie today announced updated efficacy and safety data from a small, randomized Phase 2, open-label study in patients with previously-treated multiple myeloma that evaluated two doses of the investigational monoclonal antibody elotuzumab in combination with lenalidomide and low-dose dexamethasone.
    on June 15, 2013     Source: Business Wire via Yahoo! Finance

  2. Immunomedics to Present at Wells Fargo Securities 2013 Healthcare Conference

    MORRIS PLAINS, N.J. -- Immunomedics, Inc. , a biopharmaceutical company primarily focused on the development of monoclonal antibody-based products for the targeted treatment of cancer, autoimmune and other ...
    on June 14, 2013     Source: GlobeNewswire via Yahoo! Finance

  3. Immunomedics Presents Epratuzumab's Mechanism of Action in Systemic Lupus Erythematosus

    MADRID, Spain -- Immunomedics, Inc. (Nasdaq: IMMU), a biopharmaceutical company primarily focused on the development of monoclonal antibody-based products for the targeted treatment of cancer, autoimmune ...
    on June 13, 2013     Source: GlobeNewswire via Yahoo! Finance

Quotes

  1. Mazumdar-Shaw, however, added that "the new growth drivers -- insulin, immuno-suppressants, branded formulations and monoclonal antibodies are building the bio-pharmaceuticals business in a more robust manner and reducing the dependence on statins".
    on Jul 19, 2006 By: Kiran Mazumdar-Shaw Source: Zee News

  2. "The Biolex team has successfully produced a wide range of human proteins and monoclonal antibodies including Plasminogen, a protein that contains multiple kringle domains similar to those in NK4," said Mr. Kunio Iwatani, Chief Executive Officer...
    on Oct 27, 2005 By: Toru Iwatani Source: PR Newswire (press release)

  3. "The use of immunological therapy involving monoclonal antibodies has revolutionized the treatment of many important diseases," said C. Thomas Caskey, MD, director/CEO of the IMM. "The bold new approach to Parkinson's disease by Drs. Chang...
    on Feb 13, 2009 By: Thomas Caskey Source: HealthNewsDigest.com

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