methotrexate methotrexate  /ˌmɛ θoʊ ˈtrɛk ˌseɪt/

Definition(s):

  • (n) toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis

Synonym(s)

Usage(s):

  1. Methotrexate-CFR treatment is begun soon after amputation.
  2. Scientists hope their findings will lead to EGCG-based drugs that have fewer side effects than methotrexate, which can cause vomiting and hair loss, among other ills.
  3. So has the fact that methotrexate, a highly poisonous substance, is of no value against other cancers unless special techniques of administration are used.

News

  1. Biological treatment not superior to conventional therapy for effect on work loss in patients with rheumatoid arthritis

    Treatment with a biological agent was not superior to conventional treatment in terms of the effect on work loss over 21 months in patients with early rheumatoid arthritis (RA) who responded insufficiently to methotrexate, according to a new report.
    on July 2, 2013     Source: Science Daily

  2. Treatments for Rheumatoid Arthritis and Subsequent Work Loss

    Treatment with a biological agent was not superior to conventional treatment in terms of the effect on work loss over 21 months in patients with early rheumatoid arthritis (RA) who responded insufficiently to methotrexate, according to a report published by JAMA Internal Medicine, a JAMA Network publication.
    on July 2, 2013     Source: Newswise

  3. The effect on work loss of different treatments for rheumatoid arthritis

    Treatment with a biological agent was not superior to conventional treatment in terms of the effect on work loss over 21 months in patients with early rheumatoid arthritis who responded insufficiently to methotrexate, according to a report published by JAMA Internal Medicine, a JAMA Network publication.
    on July 2, 2013     Source: EurekAlert!

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cursory cursory
/ˈkɜr sə ri /