lamivudine n a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIV Usage(s) The new agreements will further lower the cost of the most affordable generic second-line ARV regimen (tenofovir (TDF), lamivudine (3TC) and lopinavirritonavir (LPVr)) by 17 . Synonym(s) 3TC