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• n  the main protein of the keratohyalin granules
  the specific target of the immune response in rheumatoid arthritis is filaggrin

News & Articles

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• First genetic mutations linked to atopic dermatitis identified in African-American children
  Two specific genetic variations in people of African descent are responsible for persistent atopic dermatitis, an itchy, inflammatory form of the skin disorder eczema. A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss-of-function mutations to Filaggrin-2, a gene that creates a protein responsible for retaining moisture and protecting ...
  Nov. 11, 2013 - EurekAlert!
• Researchers Identify First Genetic Mutations Linked to Persistent Atopic Dermatitis in African-American Children
  A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss-of-function mutations to Filaggrin-2 (FLG2), a gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.
  Nov. 11, 2013 - Newswise