A bizarre symptom was the cyanosis of her hands and feet: it ended so abruptly at the wrists and ankles that she might have been wearing blue gloves and socks.
Resultant anemia and cyanosis are "less marked" than with the use of sulfanilamide.
Adela's cough became worse, she was suffering from respiratory distress and her hands and feet were showing signs of cyanosis that is, they were turning blue.