chondrodystrophy n an inherited skeletal disorder beginning before birth; cartilage is converted to bone resulting in dwarfism Usage(s) And when he was five, the trouble was diagnosedchondrodystrophy, a rare form of nonhereditary dwarfism believed to be caused by a chemical imbalance during gestation. Synonym(s) achondroplasia achondroplasty osteosclerosis congenita