acromegalic s marked or affected by enlargement or hypertrophy of the extremities or the face a protruding acromegalic jaw Usage(s) Up close he has the physiognomy of Rondo Hatton, the actor whose acromegalic face got him roles as villains in 40s mysteries and horror films. In Manhattan monstrous, acromegalic Primo Camera appeared before a referee in bankruptcy, sequel to a breach of prom ise verdict for $14,380.